Calcium - sensing receptor inhibits secretagogue - induced electrolyte secretion by intestine 1 via the enteric nervous system
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چکیده
Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine 1 via the enteric nervous system 2 3 Sam X. Cheng 4 5 Department of Pediatrics, School of Medicine, Yale University, 333 Cedar Street, New Haven, 6 CT 06520, USA 7 8 Running title: Calcium-sensing receptor in enteric nerves 9 10 11 Address correspondence to: 12 13 Sam X Cheng, MD, PhD 14 Department of Pediatrics 15 Yale University School of Medicine 16 333 Cedar Street 17 New Haven, CT 06520 18 Email: [email protected] 19 Phone: 203 785 4649 20 Fax: 203 737 1384 21 22 23 Articles in PresS. Am J Physiol Gastrointest Liver Physiol (April 19, 2012). doi:10.1152/ajpgi.00425.2011
منابع مشابه
Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system.
Bacterial toxins such as cholera toxin induce diarrhea by both direct epithelial cell generation of cyclic nucleotides as well as stimulation of the enteric nervous system (ENS). Agonists of the extracellular calcium-sensing receptor (CaSR) can reduce toxin-stimulated fluid secretion in ENS-absent colonic epithelial crypts by increasing phosphodiesterase-dependent cyclic-nucleotide degradation....
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